Man and machine can now be linked more intimately than ever, according to a new article in the journal ACS Nano Letters. Scientists have embedded a nano-sized transistor inside a cell-like membrane and powered it using the cell's own fuel, reports msnbc news.
The research could lead to new types of human-machine interactions where embedded devices could relay information about the inner workings of disease-related proteins inside the cell membrane, and eventually lead to new ways to read, and even influence, brain or nerve cells.
"This device is as close to the seamless marriage of biological and electronic structures as anything else that people did before," said Aleksandr Noy, a scientist at the University of California at Merced who is a co-author of the recent ACS Nano Letters report. "We can take proteins, real biological machines, and make them part of a working microelectronic circuit."
To create the implanted circuit, the UC scientists began with a simple transistor, an electronic device that is the heart of nearly every cell phone and computer on the planet. Instead of using silicon, the most common material used in transistors, the scientists used a next-generation material known as a carbon nanotube, a tiny straw-shaped material made from a single curved layer of carbon atoms arranged like the panels of a soccer ball.
The scientists then coated the carbon nanotube transistor with a lipid bilayer, basically a double wall of oil molecules that cells use to separate their insides from their environment. The scientists didn't use an actual cell membrane, however.
Could transistors treat disease?
The new enzyme-transistor link could eventually help monitor and even treat diseases and conditions, said Willner.
Some of the most obvious medical conditions the embedded transistor could help study, or alleviate, are toxins and poisons. Many of these chemicals puncture cell membranes and cause the cell's inner fluid, or cytoplasm, to leak out, essentially bleeding the cell to death. Other toxins create ion imbalances inside the cells, which can cause paralysis and other conditions.
If the cells could be encouraged to pump the necessary ions into or out of the cell, that could help treat a specific condition. However, any actual treatment based on this technology is still years away, said Willner.
"We don't want to just sense things, we also want to treat them," said Willner.
